Deep Sixed is the second game developed by Little Red Dog Games. It is a space survival simulation that borrows elements of resource management from games like FTL and time-constrained puzzle solving from games like Keep Talking And Nobody Explodes. The game was designed to place equal emphasis on spacecraft maintenance and repair as it does space combat.

Deep Sixed is a roguelike with permadeath. Players must balance competiting priorities of ship disasters, exterior threats, upgrades and supply maintenance.